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Research-informed protocol

Protocol
Guide

A practical, research-informed approach to dosing, cycling, and bottle usage.

What this is

This guide covers intranasal use of Semax and Selank, based on Russian clinical research patterns, common experimental protocols, and real-world nasal spray delivery constraints.

There are no FDA-approved dosing standards. Everything here should be viewed as informed guidance — not medical prescription.

Your base solution

If you mixed 10mg Semax + 10mg Selank in 10mL bacteriostatic water, your concentration is:

Semax1 mg/mL
Selank1 mg/mL
~0.1 mL per spray~100 mcg Semax + 100 mcg Selank per spray

Effective dose range

Semax300 – 900 mcg/daySplit into 1–3 doses/day · Clinical use: 10–14 day courses
Selank300 – 800 mcg/daySplit into 2–3 doses/day · Stress, cognitive modulation

Translation to your spray: 1 spray = 100 mcg each. 3–6 sprays/day sits inside the range used in the research.

Simple daily protocol

Morning1 spray per nostril2 total
Midday / afternoon1–2 additional sprays
Total3–4 sprays/day

This lands you at ~300–400 mcg Semax + ~300–400 mcg Selank — squarely inside the most consistently used research range.

Cycling strategy

Evidence-aligned10–14 days onThen 2–4 weeks off
Performance-oriented5 days on / 2 days offRun for 3–4 weeks, then take 2+ weeks off completely

What to avoid

  • Continuous daily use for months (no real data)
  • Blind "4 on / 3 off forever" cycles
  • Escalating dose to chase effects

If you need to increase dose to feel anything, that's already a signal to stop.

Bottle longevity

Capacity10 mL ≈ 100 sprays
At 3–4 sprays/day~25–33 days per bottle

This is the sweet spot: steady dose, clean monthly usage, no overuse.

What effects should actually feel like

Semax
  • Increased mental clarity
  • Better task switching
  • Subtle stimulation (not jittery)
Selank
  • Less background tension
  • Smoother emotional baseline
  • Less stress reactivity

Red flags

Stop or reassess if you notice:

  • Diminishing effects within days
  • Needing higher doses quickly
  • Emotional flattening or apathy
  • Headaches or irritability

These compounds aren't meant to be "felt" strongly — they're meant to quietly improve function.

Bottom line

The most defensible, research-aligned setup:

Dose3–4 sprays/day
Amount~300–400 mcg each peptide daily
Cycle10–14 days ON
BreakFull break between runs
Real effectMinimal tolerance riskSustainable long-term use

This guide is for informational and research purposes only. Consult a healthcare professional before use. Individual responses vary. Nothing here constitutes medical advice.

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